Infants with Pentalogy of Cantrell can have a wide variety of congenital heart defects including a 'hole in the heart' and abnormal location of the heart on the right side of chest instead of the left, among others.
The exact cause of Pentalogy of Cantrell is unknown. One theory suggests that the symptoms of Pentalogy of Cantrell occur due to an abnormality in the development of embryonic tissue early in the pregnancy.
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